The Quinacrine sterilization procedure requires two insertions of Quinacrine pellets into the uterus. The insertions are performed four weeks apart to ensure the best results from the procedure.
The First Insertion
QS procedure entails 2 insertions (4 weeks apart) of 7 small Quinacrine pellets. To insert the pellets into the patient's uterus, a doctor, nurse, or midwife uses a modified IUD inserter.
The pellets dissolve within one-half hour, and the Quinacrine that they release flows into the patient's fallopian tubes. Any Quinacrine that does not flow into the fallopian tubes is absorbed into the womb or flows out through the vagina.
The Quinacrine inflames the lining of the fallopian tubes. Over the next 6-12 weeks, the inflammation from the Quinacrine causes plugs of scar tissue to form at the first part of the fallopian tubes. These plugs close the tubes and block the egg’s path to the uterus.
Because it takes 6-12 weeks for the scar tissue to form, the patient must use another contraceptive method for three months, starting the day of her first insertion.
The Second Insertion
The doctor administers the second insertion 6-12 days after the patient's next menstrual period begins. This is typically four weeks following the first insertion.
Two insertions greatly increase the chance that the Quinacrine sterilization will be successful and are therefore always part of a QS procedure.